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Results, 2014, download here 

 

Results, 2013, download here 


Results, 2012, download here 

 

 
THE IVF SUCCESS RATES - SANATORIUM HELIOS 2015

 

It is true that all IVF centers do not operate the same way. They do not have the same procedures, they do not use the same materials and devices, and their staff have not had their training of the same quality, and they do not produce embryos of the same quality. The price you pay for IVF is more or less similar everywhere in the Czech Republic. The health insurance companies also pay the same amount of money to all the centers. But your chance to fulfill your dream to get pregnant and to give birth to a healthy child, varies considerably, which can be clearly demonstrated on the data available on Czech IVF centers' websites.

At present there is currently no independent databasis to objectively compare success rates of individual centers. The available data are always cumulative and even outdated. That is why we always try to explain and clarify our results and reveal our data as much as possible. We conclude from our long experience and the experience gained in cooperation with the global leader in the field of IVF research by the Australian company Genea, whose exclusive licensing agreement we own for nearly 14 years.

 

Each of the IVF clinics provides the results / success differently. For clear idea we present the results of positive pregnancy tests (G +), clinical pregnancies with proven fetal heart activity (ASP +) and births (P). Unfortunately, we are not capable to get complete data on births, especially from foreign patients, so it is possible that the success rate is even slightly increased. 

 
 

Our practices are different from those of other IVF centres, mostly because we ensure:

·   Before starting the treatment, we provide a comprehensive examination of both partners (hormonal profile, immunological tests, genetic tests, sperm count and sperm function tests, etc.

·   Monitoring of stimulations with three to four regular check ups (blood collection + ultrasound examination).

·  Correct timing of egg collection. Sometimes it is necessary to prolong or shorten the length of stimulation according to the check ups' results. Therefore, we work 7 days a week. Time to adapt to achieve optimal results.

·   We always perform so called prolonged cultivation until the 5th-6th day of embryo development. In 2015, and we only transfer the blastocysts.

·   We transfer only one embryo, always after prolonged cultivation and at the correct time relative to the phase of the cycle.

·   We provide Preimplantation Genetic Screening examination in more than half of IVF cycles, which helps to eliminate genetically defective embryos from further use. To increase the success and reduce the time needed for a healthy pregnancy.

·    In more than 70 % of the cycles we freeze all quality blastocysts (ie. cryocycles), so as to increase the chance of pregnancy with transfers in natural cycles.


 

 1. The data about our IVF patients in 2015
 
 
Chart 1: The ratio of cycles with health insurance / private patients. Private patients are those, who have already undergone all the cycles to which they are entitled from their health insurance, foreigners, patients older than the limits for health insurance coverage (39+). 
 

Chart 2: More than 65% of all cycles have been the IVF cycles with one´s own eggs.

 

Chart 3 : „Younger“ and „Elder“ patients make parts of the same size.

 

Chart 4 : The distribution of age also corresponds to the ratio of  the type of stimulaton.
 

Chart : IVF patients‘ average age in 2012-2015
(without egg donors and patients of the donorship programme).

 

Chart 6 : Methods to fertilize the eggs, which were selected based on the results of the examination of both partners.

Chart 7 : Ratio of cycles with biopsy of embryos in the stage of blastocyst for PGD or PGS examination. 
 
Chart 8 : Ratio of cycles with fresh transfer – ie. Introduction of embryos  in the cycle after stimulation and cryocycles  – suitable embryos are frozen and transferred in another cycle.

 

Chart : The graph shows number of transfers, which have the patients undergone in 2015 in Sanatorium Helios within one year.

 

75 % of patients had only 1 transfer of one embryo.

 

In another part of the result analysis we compare the unique parametres just in this particular representative group – patients, who have had just 1 opportunity to get pregnant:


2. Comparison of the age of the patients


Year after year we have more and more patients with a „worse prognosis“. The patients have been older and they have undergone more unsuccesful cycles. There is an increase of patients, who come to us after an unsuccessful IVF at a different center. 

 



 

 

IVF Cycles in Sanatorium Helios Brno in 2015

 

3. Success rate of the IVF cycles
 
Some patients have 1 transfer within one year, another patients have 2, 3, or even 4. For objective calculation of an overall success rate of IVF cycles we cannot count all the transfers and patients together. Some patients have more chances (transfers), others less. In addition, most patients had in 2015 just one single embryo transfer – a fresh transfer or a frozen embryotransfer (75%) with us - see Chart 7. Given that the majority of IVF cycles performed in Sanatorium Helios have been the frozen embryocycles, even in this group the KET (76 %) prevail.
 
 
Chart 9 : The type of transfers in the group of patients, who have undergone one transfer of one embryo in 2015 in Sanatorium Helios.

 

 
Chart 10 : Comparison of success of the fresh transfers and the frozen embryo transfers (KET) - G + are positive pregnancy tests, ASP+ clinical pregnancies with fetal heart activity, P parturition, birth (birth dates are not completely full).

 

Chart 11: The overall success rate for all patients who had a transfer  of 1 embryo - G + 1 are positive pregnancy tests, ASP + clinical pregnancy evidence of the fetal heart action, P parturition (birth dates are not completely full!).


There is an evidently higher success rate of transfers of vitrified embryos (KET) in comparison to fresh transfer cycles after stimulation. The higher success rate is given by a natural cycle in which the embryos are transferred at KET, and this group also includes a higher percentage of embryos with PGS examination, which affects the success rate, too.

 

Chart 12 : Comparing the success of embryo transfers after PGS (preimplantation genetic screening) and without PGS testing in younger and elder patients - G + are positive pregnancy tests, ASP + clinical pregnancy proved by the fetus heart action , P parturition (birth dates are not quite complete). 

 

Although the resulting quality blastocysts (developmental stage of the fifth and sixth day of embryo development), and both parents are genetically healthy (having a normal karyotype), it may occur, that genetically defective embryos have been produced.

Such embryos may stop developing very early, but these faults can also be the reason why the embryo quality (in terms of development and morphology) does not catch on in the womb, or pregnancy occurs, but it is very early lost.

For elder women there is a significantly higher number of chromosomally abnormal blastocysts compared to women, who are younger. By our results in younger women (under 35 years) occurs on average about a third of genetically abnormal embryos, whilst there is almost every second embryo marked as a genetically abnormal after PGD / PGS aCGH testing among women older than 34 years.

If the embryos after PGD / PGS examination are found to be genetically abnormal, then such genetically defective embryos are excluded from further use, so as to increase the success rate and reduce the time required to achieve a healthy pregnancy. 

 

4. Success rate after more than one transfer
 

Of course we can not count only patients who have had one single embryo transfer. Sometimes it is necessary to do several transfers to achieve the success. The data for the year 2015 show, that after 3 transfers (1, 2 or 3 transfers) have delivered nearly 80 % of patients!


This following chart shows how the patients were successful in other "groups" - those who had during 2015 two transfers (94 patients), 3 transfers (27 patients), 4 transfers (9 patients) and 5 transfers (4 patients). In the "group" 4 and 5 transfers. This is a low number of such patients, so these data are not too representative.

Graph representing the overall success of all transfers that have been done in 2015.
It is obvious that the results correspond with the results of the group, where there has been only one transfer of one embryo done (see Chart 11). The data are very similar - the percentage of births completely identical. 

 

We hope that not only our results have been persuasive, 

that Sanatorium Helios is the best choice for you.

Please come and convince about it yourself.

We look forward to meeting you.


On behalf of the whole team of Sanatorium Helios 

Pavel Texl, M. D., Chief Physician



 

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tel.: 00420 605 253 690
ivf@sanatoriumhelios.cz
prim. MUDr. Pavel Texl
Head Team Physician and Managing Director
MUDr. Jakub Texl
Gynaecologist
MUDr. Zuzana Bílková
Gynaecologist
Jarmila Slámová
Matron
MUDr. Mojmír Fischer
Gynaecologist
RNDr. Katuše Gřegorčíková
Head of Medical Genetics Laboratory
RNDr. Kateřina Wagnerová
Head of Embryology Laboratory
MUDr. Veronika Kováčová
Gynaecologist
Dana Kochová
Main IVF Coordinator
MUDr. Alena Filková
Gynaecologist
RNDr. Iveta Valášková
Medical Genetics Laboratory Guarantor
MUDr. Ditta Leznarová
Clinical Geneticist
prof. MUDr. Jiří Šantavý, CSc.
Clinical Geneticist
Educational seminary

News

2017-10-20

Educational seminary

On October, the 19th an educational seminary took place in the restaurant of Sanatorium Helios.
The topics were devoted to genetics and the genetic causes of infertility.

More

Why Sanatorium Helios

 
1

Infertility diagnosis

In most cases, the probable cause of infertility is discovered. Only about one fifth of them remain unexplained. However, even for these couples, the treatment or assisted reproduction can be successful.

2

Causes of infertility

The problem is often related to the woman. The truth is that 2/3 cases are caused by the male factor and less than a third by the female factor. In some cases, both partners participate in the couple's infertility, or it remains unresolved.

3

Genea (Sydney IVF)

In the Czech Republic, the treatment of infertility is associated with assisted reproduction at a level comparable to Western Europe. All centers of assisted reproduction in the Czech Republic have, or should have, an internationally recognized quality certification known as ISO 9001.

4

Assisted reproduction

If pregnancies do not take place even after eliminating causes, or in the cases of disorders, which cannot be solved in another way, your physician may suggest to you one of the assisted reproduction methods.

5

The Cryoembryo Transfer (KET)

Cryopreservation (freezing) is a safe method of keeping embryos in cryo containers with liquid nitrogen at −196 °C. Two basic methods of cryopreservation are generally used: slow cryopreservation and vitrification.

Partner center for assisted reproduction

Sydney IVF genea
GATJC
Sanatórium Helios SK
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