What could cause the failure of the FET?

Hi!

I am 31 year old and have PCOS for last 9 years due to which my periods are irregular or dont come without medication. Husband is 36 yrs old and sperm count is good. After multiple rounds of ovulation induction using Gonal F and IUIs ,we had our first ICSI and due to over stimulation (28 eggs retrieved out of which 21 got fertilised) we didnt have a fresh transfer plan. After a month a FET was done (5 day 3AA blastocyst) which failed and then the second FET (5 day early blastocyst) was done but also failed. Can you please let me know what could be causing this and what tests can improve the chances.

Thanks in advance

Christie

Dear Ms. Christie,

it is the quality of the embryo, which is mainly responsible for the success. Especially its genetic equipment. However, it is not possible to investigate all faults one hundred percent. Each transferred embryo has a chance of about 50 %. After 3 embryo transfers, about 70 % of patients should be pregnant.

Before your transfers, I recommend undergoing the test for celiac disease and chlamydia trachomatis, which can be the cause of a failure. Immunology does not play a big role in transfer. It is also recommended to examine the genetics of the partners before starting their own IVF.

If everything goes well, then proceed with the transfers of the remaining embryos.

Best regards